Is Medicube Zero Pore Pad 2.0 Safe During Pregnancy? (Updated 2026 Guide)
Updated March 12, 2026
Medicube Zero Pore Pad 2.0
Medicube
No, Medicube Zero Pore Pad 2.0 is not recommended during pregnancy and received an F grade. It contains salix alba bark extract, a source of salicin that is flagged to avoid, as well as salicylic acid and other ingredients requiring caution.
Do not use during pregnancy. If you've already used it, don't worry - we're all learning. If it was heavy usage or large doses, please contact your OBGYN or midwife.
Pregnancy Safe is 100% independent and research driven. No companies pay to promote or sponsor products.
Stop Googling Every Product
Scan any barcode or search by name and get a clear pregnancy safety answer in seconds
Stress Less This Pregnancy
Track your pregnancy and check what’s safe
Stop Googling Every Product
Scan any barcode or search by name and get a clear pregnancy safety answer in seconds
Stress Less This Pregnancy
Track your pregnancy and check what’s safe
What Ingredients Are in Medicube Zero Pore Pad 2.0?
Medicube Zero Pore Pad 2.0 has 27 ingredients. We flagged 1 to avoid and 2 to use with caution.
citrus aurantium dulcis fruit extract
CAUTION
Citrus aurantium dulcis fruit extract is a citrus fruit used in supplements for weight loss. Citrus aurantium dulcis fruit extract requires caution because high dose exposure may raise blood pressure and heart rate.
salicylic acid
CAUTION
Salicylic acid is a beta hydroxy acid for acne treatment. Salicylic acid requires caution during pregnancy because high concentrations can produce aspirin like effects, particularly later in pregnancy.
salix alba bark extract
AVOID
Salix alba bark extract is an herbal remedy containing salicin. Salix alba bark extract should be avoided during pregnancy because it contains salicin and salicylates can cross the placenta and increase bleeding risk.
propanediol
LIKELY SAFE
Propanediol is a solvent and preservative in foods and cosmetics. Propanediol is considered likely safe at typical cosmetic exposures, although pregnancy may reduce the body's ability to process it.
tocopherol
LIKELY SAFE
Tocopherol is a fat soluble antioxidant Vitamin commonly found in prenatal supplements and vegetable oils. Tocopherol is considered likely safe in typical cosmetic use, while excessive exposure during early pregnancy may present concerns.
butylene glycol
SAFE
Butylene glycol is a versatile, colorless, and odorless solvent and humectant commonly used in skincare and cosmetic formulations to help retain moisture and improve product texture. Butylene glycol is listed as safe for pregnancy in this formula and functions as a moisturizing solvent.
centella asiatica extract
SAFE
Centella asiatica extract is a natural plant extract known for its soothing, healing, and anti aging properties, commonly used in skincare products. Centella asiatica extract is listed as a pregnancy safe, soothing botanical in this formula.
chamaecyparis obtusa leaf extract
SAFE
Chamaecyparis obtusa leaf extract is a natural botanical ingredient known for its antioxidant, anti inflammatory, and skin soothing properties. Chamaecyparis obtusa leaf extract is listed as safe for pregnancy in this formula.
cinnamomum cassia bark extract
SAFE
Cinnamomum cassia bark extract is a natural compound derived from the bark of the cassia tree, commonly used for its warm, spicy aroma and potential health benefits. Cinnamomum cassia bark extract is listed as safe for pregnancy in this formula.
citrus aurantifolia fruit extract
SAFE
Citrus aurantifolia fruit extract is a natural extract derived from lime fruit, known for its refreshing scent and skin brightening, antioxidant properties. Citrus aurantifolia fruit extract is listed as safe for pregnancy in this formula.
citrus limon fruit extract
SAFE
Citrus limon fruit extract is a natural extract derived from lemon peel and pulp, known for its brightening, antioxidant, and refreshing properties in skincare and cosmetic products. Citrus limon fruit extract is listed as safe for pregnancy in this formula.
ethyl hexanediol
SAFE
Ethyl hexanediol is listed as safe for pregnancy in this formula.
eucalyptus globulus leaf oil
SAFE
Eucalyptus globulus leaf oil is a fragrant essential oil derived from the leaves of the eucalyptus tree, known for its refreshing aroma and respiratory soothing properties. Eucalyptus globulus leaf oil is listed as safe for pregnancy in this formula, although fragrant oils may irritate sensitive skin.
glycerin
SAFE
Glycerin is a colorless, odorless, and sweet tasting humectant commonly used in skincare products to attract and retain moisture in the skin. Glycerin is listed as a pregnancy safe humectant that helps retain skin moisture.
lactobacillus soybean ferment extract
SAFE
Lactobacillus soybean ferment extract is listed as safe for pregnancy in this formula.
oenothera biennis flower extract
SAFE
Oenothera biennis flower extract is listed as safe for pregnancy in this formula.
origanum vulgare leaf extract
SAFE
Origanum vulgare leaf extract is a natural extract derived from oregano leaves, known for its antioxidant, antimicrobial, and anti inflammatory properties. Origanum vulgare leaf extract is listed as safe for pregnancy in this formula.
panthenol
SAFE
Panthenol is a moisturizing and soothing ingredient commonly used in skincare and haircare products to improve hydration and promote healthy skin and hair. Panthenol is listed as a pregnancy safe moisturizing and soothing ingredient.
pinus palustris leaf extract
SAFE
Pinus palustris leaf extract is listed as safe for pregnancy in this formula.
portulaca oleracea extract
SAFE
Portulaca oleracea extract is a natural botanical ingredient known for its antioxidant, anti inflammatory, and skin soothing properties. Portulaca oleracea extract is listed as a pregnancy safe, skin soothing botanical in this formula.
pueraria lobata root extract
SAFE
Pueraria lobata root extract is a natural botanical ingredient known for its potential to support skin elasticity and reduce the appearance of aging. Pueraria lobata root extract is listed as safe for pregnancy in this formula.
pyrus malus fruit extract
SAFE
Pyrus malus fruit extract is a natural ingredient derived from Apple fruit, commonly used for its antioxidant and skin soothing properties. Pyrus malus fruit extract is listed as a pregnancy safe antioxidant and soothing ingredient.
scutellaria baicalensis root extract
SAFE
Scutellaria baicalensis root extract is a natural antioxidant and anti inflammatory ingredient derived from the roots of the Chinese skullcap plant, commonly used in skincare and herbal Medicine. Scutellaria baicalensis root extract is listed as safe for pregnancy in this formula.
sodium hyaluronate
SAFE
Sodium hyaluronate is a powerful hydrating agent that helps retain moisture in the skin, promoting plumpness and elasticity. Sodium hyaluronate is listed as a pregnancy safe hydrating ingredient.
ulmus davidiana root extract
SAFE
Ulmus davidiana root extract is listed as safe for pregnancy in this formula.
vitis vinifera fruit extract
SAFE
Vitis vinifera fruit extract is a natural antioxidant rich ingredient derived from grapevines, commonly used in skincare for its anti aging and skin soothing properties. Vitis vinifera fruit extract is listed as a pregnancy safe antioxidant ingredient.
water
SAFE
Water is a clear, tasteless, and essential liquid that sustains all known forms of life. Water presents no identified pregnancy concern in this formula.
Answering Your Questions
How much Medicube Zero Pore Pad 2.0 is safe during pregnancy?
The safest amount during pregnancy is none because this product contains salix alba bark extract. If you have already used it, stop using it and ask your prenatal healthcare professional if you are concerned.
Can you use Medicube Zero Pore Pad 2.0 daily while pregnant?
Avoid using this product throughout pregnancy unless your healthcare professional specifically advises otherwise. Choose a pregnancy compatible alternative without willow bark extract or other salicylates for regular skincare.
Why did Medicube Zero Pore Pad 2.0 receive an F grade?
It received an F because it contains salix alba bark extract, an ingredient flagged to avoid during pregnancy. Willow bark contains salicin, and salicylate exposure raises pregnancy related bleeding concerns.
Does Medicube Zero Pore Pad 2.0 contain salicylic acid?
Yes. Salicylic acid appears in the ingredient analysis, along with salix alba bark extract, another source of salicylate related concern.
Can I use Medicube Zero Pore Pad 2.0 while breastfeeding?
Breastfeeding exposure differs from pregnancy exposure, but this formula still contains salicylic acid and willow bark extract. Ask your healthcare professional before use, and do not apply it on or near the nipple where an infant could ingest it.
What can I use instead during pregnancy?
Look for a gentle, pregnancy compatible Toner pad or hydrating treatment that does not contain willow bark extract, salicylic acid, or other salicylates. If your skin is reactive, a fragrance free formula without essential oils may also be a better choice.
Can Medicube Zero Pore Pad 2.0 cause side effects?
Exfoliating ingredients such as salicylic acid can cause dryness, redness, flaking, or irritation, especially with frequent use or on sensitive skin. The botanical and essential oil ingredients may also be irritating for some people.
Is Medicube Zero Pore Pad 2.0 suitable for acne prone skin?
Salicylic acid can exfoliate pores, but the formula also contains botanical extracts and eucalyptus oil that may not suit reactive or acne prone skin. During pregnancy, its F grade and willow bark content make a pregnancy compatible alternative the better choice.
How Does Medicube Zero Pore Pad 2.0 Compare to Other Skin Care Pads?
We graded 1 Skin Care Pads for pregnancy safety. Here's how they stack up:
Medicube Zero Pore Pad 2.0 earns a F grade, placing it among the majority of Skin Care Pads. Only 0% of products in this category get an A grade, so it pays to choose carefully.
How Do We Score Products for Pregnancy Safety?
We analyze each product's ingredients and category to flag known risks and provide cautionary notices for general category safety concerns.
A - Safe
Excellent choice! All ingredients are considered safe during pregnancy.
What to do: Use with confidence.
B - Likely Safe
Pretty much safe with very minimal risk. Some ingredients may have limited pregnancy studies, but no significant safety concerns have been identified.
What to do: Use with confidence.
C - Limit
Contains ingredients with some pregnancy considerations. Research shows these ingredients may have limited safety data, potential for minor hormonal effects, or require caution based on animal studies.
What to do: Use sparingly and consider safer alternatives when available.
D - Caution
Similar to C grade but contains multiple cautionary ingredients. The combination increases overall concern.
What to do: Try to avoid if that makes you feel better. If you've already used it, no need to panic.
F - Avoid
Contains ingredients with established risks during pregnancy. Research shows these can cause birth defects, developmental harm, or serious maternal complications.
What to do: Do not use during pregnancy. If you've already used it, don't worry - contact your OBGYN if concerned.
People Also Checked
References
- https://www.rxlist.com/supplements/bitter_orange.htm
- https://www.scielo.br/j/aabc/a/pkCgwkXxd4SWdKNSQnBhyCh/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3129698/
- https://www.nutritionaloutlook.com/view/fda funds bitter orange toxicology study
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4177623/
- https://www.sciencedirect.com/science/article/abs/pii/S0273230017302994
- https://www.healthline.com/nutrition/bitter orange
- https://www.sciencedirect.com/science/article/pii/S1028455925000865
- http://www.anses.fr/en/content/today anses publishes its recommendations dietary supplements weight loss containing p
- https://www.peacehealth.org/medical topics/id/hn-3906002
- https://www.scielo.br/j/aabc/a/pkCgwkXxd4SWdKNSQnBhyCh/?lang=en&format=pdf
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9859859/
- https://motherfigure.com/pregnancy lactation/bitter orange citrus aurantiu/
- https://www.rivm.nl/bibliotheek/rapporten/2017-0069.pdf
- https://www.govinfo.gov/content/pkg/GOVPUB HE20_7250-PURL LPS112595/pdf/GOVPUB HE20_7250-PURL LPS112595.pdf
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4102991/
- https://www.webmd.com/vitamins/ai/ingredientmono-976/bitter orange
- https://www.nccih.nih.gov/health/bitter orange
- https://pubmed.ncbi.nlm.nih.gov/35855386/
- https://ijcbnm.sums.ac.ir/article_48337.html